Why I (Still) Use Ovasitol - Combo Myo/D-chiro Supplement - PCOS Diva
Why I (Still) Use Ovasitol – Combo Myo/D-chiro Supplement

Ovasitol

Update: Since I originally published this article, Ovasitol has been improved! The manufacturer, Theralogix, has removed maltodextrin (an excipient) from the formula, and left all of the active ingredients and the 40:1 ratio of myo to d-chiro inostiol the same. They also changed the old boxed packaging with a new resealable bag that ships better and takes up less space. I love a company that not only produces a top quality product but listens to its customers! And yes, I still take Ovasitol every day.

Like many women with Polycystic Ovarian Syndrome (PCOS), I work hard to keep my blood sugar balanced, cycles regular and testosterone levels low through diet, lifestyle and supplements. For a while, I also took inositol in the form of D-chiro-inositol (Chiral Balance) in the morning and Myo-inositol (Ovaboost) in the evening with good results.

But now…

I have replaced this regimen with one product new to the market. Ovasitol (from Theralogix) is the first product available which combines two important types of inositol, myo-inositol (MYO) and D-chiro-inositol (DCI), in one package. Its unique combination of two important inositols in a ratio that matches our body’s natural levels, is on the cutting edge of PCOS research, and many agree that, together with diet and exercise, it should be a “first line” approach to promote menstrual regularity and normal ovarian function.

What is inositol?

Inositol has been a hot topic of discussion for some time. For some background, you can refer to my previous articles, interviews and research here. In a nutshell, inositol is not a drug; it is a class of B-vitamins that naturally occur in many of the foods we consume such as fruits, legumes, vegetables, nuts, buckwheat and beans.

Two of the 9 forms of inositol (MYO and DCI) have special insulin sensitizing capabilities and are important “second messengers” for insulin receptors. You will notice that supplement dosages of MYO are always higher than for DCI; that is because your body converts MYO into DCI. These inositols are critical players in insulin signaling, and the disruption in this signaling, due to a lack of one or the other, leads researchers to believe that inositol is a key component in insulin resistance.

Unfortunately, women with PCOS have a breakdown in this process. Our bodies have difficulty converting inositol from our food into MYO and DCI, or we excrete too much DCI and cannot produce enough to replace it. This causes the breakdown in insulin processing.

As you may know, insulin resistance (IR) triggers increased testosterone. IR and high testosterone are common symptoms in women with PCOS, which cascade into a host of hormone related health issues ranging from difficulty with fertility to acne and hair loss.

Studies have shown that women with PCOS who take an inositol supplement each day will reduce their insulin resistance, improve their hormone levels, and have more regular menstrual cycles. Inositol supplementation also supports normal lipid (blood fat) levels and promotes egg quality in women trying to become pregnant.

In addition, inositol is a lipotropic agent which helps your body remove fats from your organs and blood. While inositol is most commonly thought of for restoring menstrual cycles and fertility, replacing clomiphene or metformin, current research promises a role well beyond these symptoms.

What does Myo-inositol do?

An ovarian deficiency in MYO has been linked closely to PCOS. MYO supplementation seems to help alleviate common PCOS symptoms such as insulin resistance and ovarian function issues.

In fact, MYO has been shown to improve insulin resistance and egg quality, and may reduce the risk of gestational diabetes. In fact, a 2007 study in Italy found that, “MYO is a simple and safe treatment that is capable of restoring spontaneous ovarian activity and consequently fertility in most patients with PCOS.” In another study, after only 12 weeks, patients had improved insulin sensitivity and androgen levels and returned to normal menstrual cycles . Later, in a double-blind study, researchers discovered that when given MYO, patients’ ovulation increased and they returned to normal progesterone levels.

Due to the decreases in insulin and androgen levels when patients take MYO, it is also believed to help reduce hirsutism and acne .

Studies also find that subjects receiving MYO saw decreases in testosterone, triglycerides and blood pressure .

In addition, it has been linked to the activation of serotonin receptors which may help lessen appetite, depression and anxiety while it improves mood.

While benefits were less dramatic with obese women, they did lose a significant amount of weight and lowered leptin levels. In summary, supplying extra MYO seems to  correct the malfunctioning pathways and alleviate these common PCOS symptoms.

What does D-chiro-inositol do?

Just like MYO, DCI plays a key role in mediating the action of the  insulin receptor. There is evidence that in the peripheral tissues of  women with PCOS, not enough DCI is produced from MYO, leading to a relative deficiency of DCI.  This may be what causes women with PCOS to develop insulin resistance.

Insulin resistance  causes many issues, including high blood sugar, high insulin levels, high androgen levels, and the production of too much testosterone. The excess testosterone cascades into further symptoms including belly fat, facial hair, hair loss, acne and lack of ovulation.  Increasing DCI in the peripheral tissues has been widely proven to address many of these issues, as well as improve ovulatory function (though MYO is more effective with ovulation).

D-Chiro-inositol works its magic by increasing “the action of insulin in patients with the polycystic ovary syndrome, thereby improving ovulatory function and decreasing serum androgen concentrations, blood pressure, and plasma triglyceride concentrations .”

Studies show that in women with PCOS, replacing the lost DCI with a supplement, “improved their insulin resistance and clinical features. ” Caution is necessary with DCI; women with PCOS appear to actually have too much DCI in their ovarian tissue, so  supplementing  higher doses (600-2400 mg daily) of  DCI “progressively worsens oocyte quality and ovarian response.”

Ovasitol for PCOSWhy put MYO and DCI together?

As with so many things in your body, it is all about balance. The natural ratio of MYO to DCI in your plasma is 40:1. The goal is to maintain that ratio for optimal performance. Adding too much of one or the other will throw off your balance and then you are back to square one.

Studies show that, “MI/DCI in a combination reproducing the plasma physiological ratio (40:1), represents a promising alternative in achieving better clinical results, by counteracting PCOS at both systematic and ovary level.” In fact, a recent study revealed that,  “Myo-inositol+D-chiro-inositol showed significantly better results in terms of weight reduction, resumption of spontaneous ovulation, and spontaneous pregnancy than Metformin in polycystic ovary syndrome patients.”

In addition, women with PCOS undergoing IVF may especially benefit, whereas one study found that, “only the combined therapy was able to improve oocyte and embryo quality as well as pregnancy rates.”

So, in summary, “The combined administration of MI and DCI in physiological plasma ratio (40:1) should be considered as the first line approach on PCOS overweight patients, being able to reduce the metabolic and clinical alteration of PCOS and, therefore, reduce the risk of metabolic syndrome.”

Are there any side effects to taking inositol?

The short answer is no. Occasionally, at a very high dose of MYO, one may experience mild GI side effects such as nausea, gas or diarrhea . It should not interact with your other medications or supplements. During pregnancy, you may continue taking inositol, and studies show that it may reduce gestational diabetes. As always, please consult your healthcare team before beginning any medication or supplement.

Where can I find MYO and DCI together?

A new product called Ovasitol (by Theralogix) has just come onto the market and promises to promote menstrual regularity and normal ovarian function.* Ovasitol is the first “combined inositol” supplement for women with PCOS.

I am excited about this new option because it not only combines MYO and DCI, but it does so at an ideal ratio, mimicking healthy blood plasma. This optimal combination will improve insulin sensitivity and promote normal hormone levels which can restore menstrual regularity and enhance ovary function.

Ovasitol contains 100mg of DCI and 4000 mg of MYO. The DCI is a purposefully lower dose than I have been taking as well, since the 600 mg dose in light of new research, may be too high.

Ovasitol does not contain folic acid since if you are pregnant or trying to conceive, that is already in your prenatal vitamin and too much can be damaging. I do not advocate supplementing with folic acid at any rate; I suggest using folate. This is the reason I did not use the inositol supplement Pregnitude.

For more information on folic acid and folate, read my article here.

My former regimen of Ovaboost and Chiral Balance was $263.85 ($86.85 for Ovaboost and $177 for Chiral Balance) for 3 months. Ovasitol will cost me $78 for the same timeframe.  The downside, if you are trying to get pregnant, is the loss of folate, melatonin and the antioxidants contained in Ovaboost that can support egg quality.

I also like the portability of Ovasitol. It comes in easy to use packets and is tasteless, odorless and dissolves easily in water, so I can slip it in my purse and take it on the go!

I am confident taking Ovasitol because it is produced in a thoughtful way by a reputable company. Theralogix formulated Ovasitol with an advisory board of leading reproductive specialists, and it was vetted by NSF® International (a non-profit certification program) for purity, content accuracy and freedom from contaminants. Inositols are relatively unregulated nutritional supplements. This means there is no one monitoring for variance between batches of a product or even contamination by other substances. Voluntary third party monitoring reassures me of Theralogix’s commitment to a quality product.

A healthy diet and lifestyle are always required for optimal health, but in a case like this when our body’s systems cannot derive nutrients from the food we eat, supplements are definitely a good choice.

I encourage you to talk to your health care team about adding Ovasitol to your regimen. Work on inositols is cutting edge, and these studies are small. Your team may be unfamiliar with the research. Take information with you to share, and take control of your health.

 

If you are interested in ordering Ovasitol, you may do so here and automatically receive the lowest price.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Resources:

Abdel, Hamid, Mohamed S. Amr, Madkour Ismail, A. Wael, and Wael Borg. “Inositol versus Metformin Administration in Polycystic Ovary… : Journal of Evidence-Based Women’s Health Journal Society.” Evidence Based Women’s Health Journal. Lippincott Williams & Wilkins, Aug. 2015. Web.

Artini et al. Endocrine and clinical effects of myo-inositol administration in polycystic ovary syndrome. A randomized study. Gynecol Endocrinol. 2013; 29(4):275-9. 6.

Baillargeon JP M.D., M.Sc.,corresponding author Maria J. Iuorno, M.D., M.Sc., Teimuraz Apridonidze, M.D., M.Sc., and John E. Nestler, M.D. “Uncoupling Between Insulin and Release of a d-Chiro-Inositol–Containing Inositolphosphoglycan Mediator of Insulin Action in Obese Women With Polycystic Ovary Syndrome.” National Center for Biotechnology Information. April 8, 2010. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140116/ (accessed October 24, 2014).

Brink CB, et al. “Effects of myo-inositol versus fluoxetine and imipramine pretreatments on serotonin 5HT2A and muscarinic acetylcholine receptors in human neuroblastoma cells.” Metabolic Brain Diseases, 2004.

Carlomagno G, et al. “Inositol safety: clinical evidences.” European Review for Medical and Pharmacological Sciences, 2011: 931-6.
Colazingari S, et al. “The combined therapy myo-inositol plus D-chiro-inositol, rather than D-chiro-inositol, is able to improve IVF outcomes: results from a randomized controlled trial.” Archives of Gynecology and Obstetrics, 2013: 1405-11.

Constantino D, et al. “Metabolic and hormonal effects of myo-inositol in women with polycystic ovary syndrome: a double-blind trial.” European Review for Medical and Pharmacological Sciences, 2009: 105-10.

Dinicola S, et al. “The rationale of the myo-inositol and D-chiro-inositol combined treatment for polycystic ovary syndrome.” Journal of Clinical Pharmacology, 2014: 1079-92.

Genazzani AD, et al. “Myo-inositol administration positively affects hyperinsulinemia and hormonal parameters in overweight patients with polycystic ovary syndrome.” Gynocological Encocrinology, 2008: 139-44.

Iuorno MJ, et al. “Effects of d-chiro-inositol in lean women with the polycystic ovary syndrome.” Endocrine Practice, 2002: 417-23.
Kumar SM, et al. “Molecular level interaction of the human acidic fibroblast growth factor with the antiangiogenic agent, inositol hexaphosphate.” Biochemistry, 2010.

Laganà AS. “Myo-Inositol Vs D-Chiro- Inositol: preliminary data on the comparison between their effects on ovarian function and metabolic factors in women with PCOS.” Proceedings of The World Congress on Building Consensus out of Controversies in Gynecology, Infertility and Perinatology . IStanbul, Turkey, 2013.

Larner J, et al. “D-chiro-inositol glycans in insulin signaling and insulin resistance.” Mol Med. Nov-Dec 2010. http://molmed.org/journal/articles/1/32 (accessed October 24, 2014).

Nestler JE. “Ovulatory and metabolic effects of D-chiro-inositol in the polycystic ovary syndrome.” New England Journal of Medecine, 1999: 1314-20.

Nordio M, et al. “The combined therapy with myo-inositol and D-chiro-inositol reduces the risk of metabolic disease in PCOS overweight patients compared to myo-inositol supplementation alone.” European Review for Medical and Pharmacological Sciences , 2012: 575-81.

Papaleo et al. Myo-inositol may improve oocyte quality in intracytoplasmic sperm injection cycles. A prospective, controlled, randomized trial. Fertil Steril. 2009; 91(5):1750-4.

Rosalbino I, et al. “Does ovary need D-chiro-inositol?” Journal of Ovarian Research, 2012.

Unfer et al. Effect of a supplementation with myo-inositol plus melatonin on oocyte quality in women who failed to conceive in previous in vitro fertilization cycles for poor oocyte quality: a prospective, longitudinal, cohort study. Eur Rev Med Pharmacol Sci. 2011; 15:452-7. 10.

Vireday, Pamela. “PCOS Treatment: The Inositols.” Well Rounded Mama. october 31, 2013. http://wellroundedmama.blogspot.com/p/about-this-blog.html (accessed october 24, 2014).

Zacchè MM, et al. “Efficacy of myo-inositol in the treatment of cutaneous disorders in young women with polycystic ovary syndrome.” Gynocological Endocrinology, 2009: 508-13.

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  • Abbie

    Has anyone else been having issues with ordering? I can place it in my cart but, when I try to go to checkout, it won’t load the proper page.

    • Courtney

      I am having the same problem, it just keeps going back to the cart…

  • Karina

    Does anyone have the Provider Referral Code (PRC) to receive the discount? It was in the article when I first read it but know I can’t seem to find it!

    • Britt

      40762

  • Staceyh1207

    Hello, can you ship products to Australia?

    • Amy Anderson Medling

      Hi Stacey, This is not a PCOS Diva product. I just wrote a review. You can always contact the manufacturer. Good luck!

  • Guest

    Seems like many of you are having an issue with ordering. I read this article on 11/10/14 and placed my order that same day by clicking the link in “If you are interested in ordering Ovasitol, you may do so here and automatically receive the lowest price.”
    When I added the product to my cart it automatically gave me the provider discount, I did not have to enter any code.

    I received my order on 11/14 and started taking the following day. So far I haven’t noticed much different but I’m sure it takes more than a few days. I also have not had any adverse side effects.

  • Blair45121

    I was able to place my order on 11/10/14 by clicking the link in “If you are interested in ordering Ovasitol, you may do so here and automatically receive the lowest price.” comment. When I added the product to my cart it automatically gave me the provider discount, I did not have to enter any code.

    I received my order on 11/14 and started taking the following day. So far I haven’t noticed much difference but I’m sure it takes more than a few days. I also have not had any adverse side effects. I’ll be starting my 2nd IVF this coming spring and I’m hopeful that I will start noticing some changes soon that will help improve my IVF success!

    • KK

      I am thinking about taking ovasitol, and am on the ivf path, curious to know how things have gone for you. do you still like it? thanks.

      • Blair45121

        Hi KK. I really can’t give an honest review as I haven’t been very faithful in taking it as directed. I seem to be good for a few weeks then slack off on taking it. Its been about 2 months since I took the last dose. When I was taking it on a regular basis I didn’t really see a difference but I think as with all supplements you need to take it for a few months before any results are seen. I didn’t experience any side effects so that was a good thing. There is a slight taste if you drink it with water but its not bad at all. I keep telling myself that I’m going to get back on track since I too plan on going for my 2nd round of IVF this fall….it just hasn’t happened yet 🙂 Best wishes to you on your journey!

  • Nya

    Pregnitude vs Ovasitol. Which is better?

    • Brittany

      Ovasitol worked way better for me. Ovasitol actually balanced out my hormones. I ovulated on my own, saw my skin clear up, and noticed that my awkward body hair had thinned.

  • Wiktoria Makuch

    Hi Amy,

    could u please help me? I bought my inositol from here:

    http://www.myprotein.com/sports-nutrition/inositol/10530319.html

    and I dint know there was something like MYO and DCI. How do I know wich one i bought?
    I m using 4g+Folid acid since 2 weeks. After reading your article I m afraid I m taking to much also not the right one.

    For a response I would be greatful.

    Greatings from Poland
    Wiktoria

  • Patricia Fearing

    Can you tell me if/how this would work in conjunction with Glucorein HOP?

    • Nancy Foti

      I would recommend that you choose one or the other, although I don’t think it would be unsafe to take both. We don’t have any reason to think taking the 4 g myo-inositol in Ovasitol + either 200 mg or 400 mg more, depending on dose of glucorein, would be too much. However, a higher dose may increase chance of stomach upset. Ovasitol should be fine to take with the other ingredients.

  • Stephanie P de Melo

    What is the difference between berberine and Ovasitol? Can you take them together?

    • Amy Anderson Medling

      Berberine is an alkaloid, which is a chemical compound found in several plants such as goldenseal. Other herbs that contain berberine are Chinese goldthread (Coptis trifolia), barberry (Berberis vulgaris), and Oregon grape (Mahonia aquifolium). It’s also found in roots, rhizomes, and the stem bark of these plants.

      Experts believe that berberine’s health benefits are connected to the way it affects AMP-activated protein kinase (AMPK). This is the enzyme that controls the way your body produces and uses energy. If the body’s AMPK levels are unbalanced, this can affect how your body regulates cholesterol, blood pressure, and blood sugar.

      Inositol is a type of B vitamin. is a class of B-vitamins that naturally occur in many of the foods we consume such as fruits, legumes, vegetables, nuts, buckwheat and beans. Two of the 9 forms of inositol (MYO and DCI) have special insulin sensitizing capabilities and are important “second messengers” for insulin receptors. These inositols are critical players in insulin signaling, and the disruption in this signaling, due to a lack of one or the other, leads researchers to believe that inositol is a key component in insulin resistance.

      • Stephanie P de Melo

        Thanks for the information. Do you recommend to take both or one opposed to the other?

  • Megan

    I just received my order and noticed that maltodextrin is on of the ingredients in this. .. I thought maltodextrin was a “no-no” for Divas? I’d love to hear your thoughts! Thank you!

    • jenni

      I also am curious as to why maltodextrin is an ingredient!?! Anyone?

      • Amy Anderson Medling

        Ovasitol is working to take the maltodextrin (used to make the powder flow out of the packet) out. They should have a new version soon.

  • Cheryl Edwards

    Can I use Ovasitol as a postmenopausal women with PCOS?

    • Amy Anderson Medling

      Yes. 🙂

  • B Herron

    I am currently TTC and taking Ovasitol and Fertilaid, but I was wondering whether I should be taking Ovaboost + DCI instead of Ovasitol bc of the other ingredients. Do you have a recommendation?

  • Ashley Aurigemma

    Hello I am trying to purchase Ovasitol but need your provider referral code. I clicked on you link but it doesn’t auto populate the code in Theralogix for the $78 price. Please help.
    Thanks 🙂

    • Nancy Foti

      It should automattically deduct the savings in she shopping cart. Here is my provider code: 909011

  • hhramblings

    I showed this article to my doctor at my last visit. She hadn’t heard of this product, but was very familiar with inositol. She thought that this looked like a great option for me to try. I’m getting ready to place my first order now and hoping for great results! Thanks for sharing. 🙂

  • just me

    Where can I purchase ovaboost?

  • Diana

    Is it okay to take Ovasitol and Metformin together?

    • Amy Anderson Medling

      Please ask your doctor or other healthcare provider about taking Ovasitol with Metformin, or taking Ovasitol instead of Metformin. Because both inositol and Metformin have been shown to affect insulin levels and restore ovulation, they may have additive effects. In one study comparing myo-inositol to Metformin, myo-inositol showed slightly better results for restoring ovulation and increasing pregnancy rates.

      CHeck out my Ovasitol FAQ for more answers: http://pcosdiva.com/2015/01/ovasitol-frequently-asked-questions/

  • Diana

    I am attempting to help my daughter who is 27 is just beginning to have increased symptoms of PCOS. She has been taking metformin for a few years now with great results. However, recently she has been having a hard time losing weight, acne has increased, and she is noticing some other symptoms. She has battled with GI issues for a while and has found great results with a prescription strength probiotic. She has been gluten free and dairy free for a couple of years which has helped with the GI issues. Would adding Ovasitol be a good option for her? We don’t even really know where to turn.

  • Gina

    I’m 63 years old…can I use Ovasitol too? It sounds as though it regulates the menstrual cycle which I don’t have anymore. I do have all the life altering PCOS symptoms though.

  • Whitney Pollan

    There was a question asked below regarding the berberine versus the Ovasitol. Am I understanding correctly that they work much in the same way but from different resources? I don’t think it was ever answered if you can take them both together or are they meant to be taken one or the other?

  • Bee Demir

    Is there any way of ordering Ovasitol in the UK?

    • Kirsty Shears

      There is now!

      Order through functional nutrition website! Got mine today 🙂

      • I would love to try this but £99 at the moment is too much, do you know where it is cheaper?

        • Kirsty Shears

          I believe that functional nutrition are the only UK stockist. I agree with you though, can’t afford it all the time. So now I’m back on Jarrow Inositol Powder until I can afford it again.

        • Hayley

          I’ve just ordered some from http://www.generalfarmacia.com, it’s the first time I’ve ever used them so ive no idea if it’s reputable or not yet but I used paypal for some level of security.

  • Su Charnock

    I want to know too, where can the UK people with PCOS purchase this Ovasitol

  • sn

    I used it for 4 months and have started having a regular period!!

  • Tasia Alexis

    Can this be taken with Chromium Picolinate 500 mcg, Saw Palmetto 500 mg, and Prozac 10mg?

  • Diana

    @pcosdiva, may I have your referral number for theralogix? I have many friends who want to order and I used to use your link to the theralogix site, but there isn’t one now. I know they can order from your site, but that doesn’t have the autoship and ease of use for customer service from Theralogix. Thanks.

    • Amy

      Hi Diana – the number is 909011

  • Samantha

    For the past two months I have been taking Ovasital -F and Metformin (bigomet SR 500). At first I did notice changes, acne gone , clear skin, weight loss but my periods have still been irregular and for the past couple weeks I seem to have a lot of flab around my stomach and makes me feel bloated. My doctor suggested Fasting Insulin test. However, I also did a fasting sugar test and it read 100 (normal range). Why am I feeling this way? I eat super healthy (quinoa , oats) fresh fruits & vegetables. I run in the morning & walk in the evening. I am fit but I feel fat. Please help.

  • NanaA

    My Ovasitol just arrived and i just noticed it had “maltodextrin” isnt that bad for people with pcos and doesnt it defeat the purpose and isn’t that counterproductive? Im concerned?

    • Amy Anderson Medling

      Ovasitol is working to take the maltodextrin (used to make the powder flow out of the packet) out. They should have a new version soon. It is a very small amount and shouldn’t disprupt blood sugar.

  • Kirsten Smith

    Hi – I’m from Australia – I notice some people from the UK and Australia asking about where to get this product. The business below is a UK business which will also ship to Australia.
    http://www.functionalnutritionsupplements.co.uk/

    • Louise Harris

      Thank You! ❤️

  • Melanie Phy

    I just have a question. I do not have PCOS but a friend of mine does and she recommended this product to me as a type 2 diabetic. Also ever since I went off birth control due to sugar issues over 2 years ago my periods have been pretty bad and painful so my question is can I use this product along with my current medication to help with my insulin resistance and blood sugar regulation?

  • Kristina

    I have been taking Ovasitol for 6 months now and I LOVE it! It has restored my cycle to 33/34 days. I am wondering however if it is okay to take both Ovasitol and Berberine together since the Ovasitol is basically a B Vitamin? I need to order more Ovasitol and am not sure if I should order Berberine or not. Thanks a bunch!

    • Amy Anderson Medling

      I take both – but check with your doctor on the berberine – you can’t take it if you are on certain meds.

      • Kristina

        Thank you Amy for your quick reply!! Luckily I am on no other medications other than a pre natal vitamin (we tried to conceive for the past 2 years and are giving it a break and we already have 3 children) Ovasitol and COQ10. I had noticed that Berberine took care of some symptoms which Ovasitol does not help. And vice versa. Berberine really helped with weight loss, acne and food cravings and Ovasitol doesn’t seem to be helping in those areas but has greatly helped my ovulatory cycle which is GREAT! Thank you for all you do Amy you are such a blessing to all of us!

  • Nur Ain

    Hi is there any way for me to order from Singapore? I am actively trying to conceive and looking the right supplements before i start my next ivf in May/June.

    • Amy Anderson Medling

      You can try the forwarding service shipito.com

  • Fairy Khan

    Assalm o alikum
    Friends plz help me,mujhy periods nhe hoty,I m married, doctor ny ovasitol recommend ke ha two months sy le rhe hn but periods nhe huwy,KB tk use kro k wo normal ruteen PA ajaien.

    • Syeda

      Wsalaam, 3 to 6 months atleast, aur aap apni diet main dairy, sugar aur gluten wali cheezain nikal dain. Exercise karain aur weight lose karain inshAllah hojaingey

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